Ovary removal and breast cancer

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What is ovarian suppression? How does it work as a treatment for breast cancer? Who might be offered ovarian suppression?

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Luckily she caught it early. It was Stage 1, Grade 2, less than 2 cm, they removed it, and some lymph nodes. The nodes were clear, as was a subsequent CT Scan.

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Prophylactic oophorectomy oh-of-uh-REK-tuh-me significantly reduces your odds of developing breast cancer and ovarian cancer if you're at high risk. Weigh the pros and cons of this cancer prevention option. Preventive surgery to remove the ovaries might be an option that people with a high risk of ovarian cancer and breast cancer might consider to reduce their risk.

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XRAYS reviews new breast cancer research, provides plain-language summaries, and rates how the media covered the topic. People with a genetic mutation linked to cancer risk. Special populations: Premenopausal women who are not at increased risk of ovarian cancer.

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Back to Hysterectomy. If you have a hysterectomy, as well as having your womb removed, you may have to decide whether to have your cervix or ovaries removed. Even if you do not have cancer, removing the cervix takes away any risk of developing cervical cancer in the future.

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Women who have the gene mutations BRCA1 or BRCA2 can reduce their likelihood of developing ovarian cancer and breast cancer by having prophylactic surgery to remove both ovaries, according to two new studies in the New England Journal of Medicine. However, because removing both ovaries substantially lowers the production of hormones, the researchers said there is some concern that hormone replacement therapy—which is required after the surgery—could raise the risk of cancer by restoring some of these hormones. The patients were followed for eight years, during which eight of the women who had their ovaries removed developed ovarian cancer or papillary serous peritoneal carcinoma, a related cancer.

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For some women who have a very high risk of breast cancer, preventive surgery to remove the breasts prophylactic mastectomy may be an option to lower their risk. Like any type of surgery, a mastectomy can have risks and side effects, some of which could affect your quality of life. Because of this, preventive surgery is not usually a good option for women who are at average risk of breast cancer, or for those who are at only slightly increased risk.

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One way to slow the growth of hormone receptor-positive breast cancer in premenopausal women is ovarian suppression. Ovarian suppression uses drug therapy or surgery to prevent the ovaries from making estrogen. This stops menstrual periods and lowers hormone levels in the body similar to a natural menopauseso the tumor can't get the estrogen it needs to grow.

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In premenopausal women, most of the estrogen in the body is made by the ovaries. Because estrogen makes hormone-receptor-positive breast cancers grow, reducing the amount of estrogen in the body or blocking its action can help shrink hormone-receptor-positive breast cancers and reduce the risk of hormone-receptor-positive breast cancers coming back recurring. This is called prophylactic or protective ovary removal, or prophylactic oophorectomy. Removing the ovaries is one way to permanently stop the ovaries from producing estrogen.

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